INTEGRATED PLATFORMS FOR THE CLARIFICATION AND CAPTURE OF MONOCLONAL ANTIBODIES

 

S.C. Bernardo, A.M. Azevedo and M.R Aires-Barros

 

 

  • Monoclonal antibodies purification using aqueous two-phase systems (ATPS) is reviewed.

  • ATPS present a biocompatible environment for biomacromolecules.

  • Large scale clarification, recovery and purification of the target product is achievable in just one step.